Following the application of the clinical de-pigmenting mask, it will need to remain on between 8-12 hours, depending on skin condition. After the required time, it may be simply removed at home.

For the next few days after removal, the skin may feel a little tight and there may be some localised flaking.

The daily use and re-application of a sunscreen is vital to ensue treatment efficacy and results. Keeping the skin well-hydrated following the removal of the Cosmelan mask is also vital to reduce unwanted dryness or flaking.